Blood transfusion reaction
Incompatibility make clumps/agglutinates.
Cells (antigen) from donor will react with recipient antibody.
One antibody can bind several antigen.
Can plug in small blood vesicles and Cell will be destroyed by macrophage or physical distortion.
Transfusion reaction
Antibody from donors not make problem due to dilution.
Can be immediate hemolysis.
Delayed hemolysis – need high titer of antibody for lysis to occur.
Can results jaundice.
Can be minor reaction to death.
AB type – ‘universal recipients’
O type – ‘universal donors’
But always need cross match.